NIH Common Fund researchers link genetic variants and gene regulation in many common diseases | Pharmaceutical Processing

NIH Common Fund researchers link genetic variants and gene regulation in many common diseases | Pharmaceutical Processing:

Researchers supported by the NIH Common Fund have discovered that genetic differences linked to a wide variety of diseases, including many adult-onset diseases, influence how genes are turned on, or activated, during fetal development. These findings may help to explain why some environmental exposures in utero or during early childhood are known to increase risk of diseases that produce symptoms years or even decades later. In addition, researchers were able to pinpoint which cell types are affected by different diseases. These results provide new insight into disease mechanisms, and suggest novel targets for therapeutics development and disease prevention strategies.